Physicians like Sir Charles Locock hypothesized that sedative drugs might calm overactive brain activity, a theory he confirmed by treating seizures with a medication called potassium bromide.

像查尔·爵士这样医生假设镇静物可能会平息度活跃大脑活动，他通使用一种叫做溴化物治疗癫痫发作证实了这一理论。